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What Are The Differences Between Reduced Glutathione And Oxidized Glutathione

Issuing time:2022-04-02 11:37

We often hear that glutathione can whiten and beautify the skin, and even be added to medicine to have some adjuvant effects, while glutathione is a combination of glutamic acid, cysteine and glycine, which has antioxidant and the detoxification effect contains thiol active peptide, which is easy to complex with heavy metal salts such as lead, mercury and arsenic in iodoacetic acid, which is its integrated detoxification effect. Our liver also contains a lot of glutathione, glutathione assists the liver in detoxification.


There are two forms of glutathione, oxidized and reduced. Under physiological conditions, L-glutathione reduced accounts for the vast majority. Glutathione reductase catalyzes the interconversion between the two types. The coenzyme of this enzyme is NADPH provided by the alternative metabolism of sugar phosphate. Below, we briefly analysis the difference between reduced glutathione and oxidized glutathione.

What are the differences between reduced glutathione and oxidized glutathione?


Reduced glutathione is a naturally synthesized peptide in human cytoplasm, widely distributed in various organs of the body, and plays an important role in maintaining the biological function of cells. It is also a coenzyme of glyceraldehyde phosphate dehydrogenase, glyoxalase and triose dehydrogenase. It can not only participate in the tricarboxylic acid cycle and sugar metabolism in the body, but also activate a variety of enzymes, which can catalyze fat or Carbohydrates, proteins, promote the metabolism of substances in the body, and speed up the process of the body's metabolism.

Moreover, l-glutathione reduced can combine with free radicals in the body through sulfhydryl groups, convert free radicals into acidic substances, and discharge them, remove excess free radicals in the body, slow down the aging of the body, and the reduction of free radicals is beneficial to anemia. , poisoning or tissue inflammation has a relieving effect, which can relieve the body's oxidative reaction. Reduced glutathione can also promote the synthesis of cells in the body, thereby nourishing the liver and protecting the liver, promoting the absorption of nutrients by the body, and improving the body. Adjuvant and preventive effects of glutathione: detoxification, radiation sickness and radiation protection, liver protection, anti-allergy, improvement of the course and symptoms of certain diseases, beauty and skin care, increased vision and eye diseases, anti-aging, etc.


Usually, glutathione mentioned in life refers to reduced glutathione. However, glutathione is extremely unstable and is easily oxidized to oxidized glutathione in the air. In order to distinguish between the two nature, we add the adjectives reduction and oxidation. Therefore, reduced glutathione and oxidized glutathione are the same thing, but the properties of the substance have changed.

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