What Is Schisandra Chinensis Extract Good For

Schisandra chinensis extract is the dried fruit extract of Schisandrachinensis, etc. The main active ingredients are lignans such as Schisandra chinensis A, Schisandra chinensis B, Schisandra chinensis alcohol A, Schisandra chinensis alcohol B, Schisandra chinensis C, Schisandra chinensis ester A, etc., and also contains Various volatile oils such as pinene and organic acid compounds such as citric acid, malic acid and tartaric acid. What Is Schisandra Chinensis Extract Good For? Let's have a look:

1. Action on the liver

Schisandra chinensis fruit extract and its preparations can promote hepatic gluconeogenesis, promote hepatic glycogen decomposition, and strengthen the glucose phosphorylation process of fructose in brain, liver and muscle; its ethanol extract can significantly reduce serum alanine aminotransferase, It has a protective effect on liver damage caused by carbon tetrachloride. After oral administration of Schisandrin (Ⅰ), the activities of liver microsomal cytochrome P-450, NADPH-cytochrome C reductase, aminopyrine demethylase, liver weight and liver microsomal protein content were significantly increased. And the activity of hydroxylase was higher than that of hydroxylase. Electron microscope observation showed that the endoplasmic reticulum of rat liver cell was significantly proliferated, which indicated that it had an induction effect on liver microsomal monooxygenase. In addition, it can reduce SGPT in CCl4-intoxicated mice, inhibit CCl4-induced hepatic microsomal lipid peroxidation, and CCl4 metabolism into CO. These effects are similar to those of other components of Schisandra chinensis, such as B.

2. Effects on the central nervous system

The crude extract of Schisandra can increase the excitability of the central nervous system, improve intellectual activity and work efficiency. Both schisandra can significantly prolong the sleep time of pentobarbitone in mice, and the two have a synergistic effect. Oral administration of pentanol to mice can significantly reduce brain activity. Its alcoholic extract has anti-electric shock and central stimulant-induced convulsions.

3. Effect on peptic ulcer

Schisandra chinensis fruit extract has a good effect on inhibiting gastric ulcer, and also has a preventive effect on gastric mucosal damage caused by anhydrous ethanol.

4. Effects on the cardiovascular system

Schisandra chinensis and its extracts have vasodilatory effects, and when the circulation is exhausted, they have a significant blood pressure boosting effect. In addition, it also has a certain cardiotonic effect. Schisandra chinensis has β-blocker effect on frog hearts in vitro and in vivo.

5. Effects on the immune system

The inhibitory effect of Schisandra chinensis alcohol extract 25mg/kg/day on mouse spleen antibody-secreting cells and specific rosette-forming cells is the same as that of corticosteroid 20mg/kg/day, and the combination of the two has obvious synergistic effect.

6. Anti-aging effect

Schisandra chinensis fruit extract has the effect of enhancing cellular immunity, enhancing the synthesis of RNA and PAS in testis and ovary, promoting the proliferation of germ cells, and has obvious anti-free radical effect. It can also play an anti-aging effect by changing the activity of MAO and its isozymes. . Schisandrin has antioxidant properties that protect the heart from damage from lipid peroxidation.

7. Effects on the kidneys

Gomisin A and deoxyschisandrin inhibited the increase in urinary protein excretion and improved serum biochemical parameters.

8. Anti-allergic effect

Gomisin A has obvious inhibitory effect on rat homologous passive allergic skin reaction (PCA) and rat skin allergic reaction.

9. Anti-tumor effect

Schisandra chinensis extract γ-schisandrin has cytotoxic effect on leukemia and KB cells, and inhibits the metabolism of cancer cell DNA, ATP and nuclear protein.

10. Antibacterial effect

A 100% aqueous solution is most sensitive to dermatophytes. The ethanol infusion of Schisandra chinensis is in vitro against Bacillus anthracis, Staphylococcus aureus, Staphylococcus albus, Paratyphoid Bacillus A and B, Pneumococcus, Typhoid Bacillus, Vibrio cholerae, Salmonella Enteritidis, Shigella Shigella, Proteus, etc. have inhibitory effect. It also has strong antibacterial effect on Pseudomonas aeruginosa. It has antiviral effects both in vivo and in vitro.